During the second half of the 20th century, there was a sharp increase in hysterectomy in the United States.
During the second half of the 20th century, there was a sharp increase in hysterectomy in the United States. Concurrent with that trend, there was an epidemic of endometrial cancer that has been att ributed to widespread use of replacement estrogens among menopausal women. Th e epidemic of endometrial cancer was not immediately evident, however, in data on endometrial cancer rates compiled from cancer registries. Devise a hypothesis based on considerations of the population at risk for endometrial cancer that can explain why the epidemic went unnoticed.
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